It’s a seemingly undeniable truth that ageing is inevitable. But what if everything we’ve been taught to believe about ageing is wrong? What if we could choose our lifespan? David Sinclair, PhD, AO, is a professor of genetics at Harvard Medical School. One of the leading innovators of his generation, he has been named by Time as “one of the 100 most influential people in the world” and top fifty most influential people in healthcare. David’s eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, ageing. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of ageing and the key to reversing it. Recent experiments in genetic reprogramming suggest that soon we may not just be able to feel younger but become younger. In this interview, I speak to Dr. David Sinclair, professor of genetics at Harvard Medical School, and author of Lifespan about why we age, why we don’t have to. We explore the technologies and simple lifestyle changes that can help us live younger and healthier for longer, and discuss David’s bold new vision for the future of humankind where we could live healthy lives over many centuries.