Each time we learn something new or encounter a fresh experience, we trigger a reconfiguration of our brains. Neuroplasticity is highest during youth, explaining why children and young adults up to the age of 25 absorb knowledge so rapidly. Their learning capacity is immense, akin to sponges soaking up water.

Opportunities generally arise from landscape change. But entrepreneurial ideas can come from anywhere. They can come from recognizing where the pain points, the bottlenecks, and the inefficiencies are. They can come from late-night conversations with friends, or from random eureka moments.

Don't give away a majority shareholding the way I had to with HomeServe. I ended up giving away 52% of the shares with my partner for a £500,000 investment we took when we'd run out of money—a terrible time to raise capital.

It's the ultimate invention—the last one we'll ever need to make—because once we have AI that is generally intelligent and then superintelligent, it will do the inventing far better than we can. In that sense, it's a handing over of the baton.

The world simply cannot manage Covid-19 without international cooperation around the production and distribution of medical equipment, research and distribution of a vaccine, and the cooperation between economies needed to ensure that we all return to growth.