We are all strategists or game theorists at heart – it took several decades of people writing-down models and articles before we recognised what we know from playing poker; we don't know our opponent's hand.

It might feel—if you haven't yet learned the rules of these hidden markets—that the outcomes are based on luck, chance, or things beyond your control, but you actually have a lot more agency in them than you think.

Coach Wooden's little lesson wasn't just about socks, but about how everything in life was basically a Rube Goldberg contraption with many seemingly unrelated parts that form a greater interrelated machine. Neglecting what appears insignificant can create a domino effect of failure.

We are scientifically naked in front of this threat. We do not have the diagnostics to quickly detect an MDR or XDR case. Once detected, we do not have the drugs to effectively treat the patient at reasonable cost, and we do not have a TB vaccine.

Without any major adjustments to our conduct and behaviour, we will see the unravelling of an informed civilisation.