In the Fourth Generation war, the state loses its monopoly on war. All over the world, state militaries find themselves fighting non-state opponents such as al-Qaeda, Hamas, Hezbollah, and the Revolutionary Armed Forces of Colombia. Almost everywhere, the state is losing.

Trust is a confident relationship with the unknown. And the reason this is so important is that trust isn't, at its essence, an asset or an attribute or a currency. It's a belief. It's what we believe about someone or something. That definition is slightly counterintuitive because, often, when people think about trust, they talk about knowing what to expect from someone or knowing what the outcomes will be. So, they're actually thinking about trust through the language of risk, thinking about it in terms of certainty. And that's not what trust is.

Stress doesn't come from what's going on in your life. It comes from your thoughts about what's going on in your life.

It feels great to have the iPad launched into the world...it's going to be a game changer.

Sleep became not just devalued but actively scorned. After all, every hour spent sleeping was another hour spent not working—therefore another wasted hour. And despite a growing awareness of the importance of well-being, so many of our modern attitudes still reflect this.

One of the great ironies of a company like Meta, where I worked, is that well over 90% of its users are outside the US, yet well over 90% of the bandwidth among decision-makers is focused on what's happening in America. In the end, that just doesn't make sense.

From cell to civilisation took about 4 billion years, which is a long time—a third of the age of the universe. If it takes billions of years to produce complex living things at our level, maybe there aren't many places that could sustain an unbroken chain of life for that long.

Remember that back in 1950, they invented something called the computer that allows you to do more complex calculations than you could with a paper and pencil. Computers allow us to use much more sophisticated statistical techniques to calculate seasonal adjustments, which mean that we do not need to use year-over-year calculations.

We don't fail because we make mistakes; mistakes can be fixed. We fail because we quit. And we quit because belief collapsed, not because the strategy was wrong.

We are under an existential threat now as humankind. Even a simple two-cell yeast has a survival instinct and evolves fast enough to try and survive. I don't understand why humans who are supposed to be these very complex creatures can see that we're heading towards a very, very dangerous future which could be irreversible, and why we're not doing absolutely everything possible now.

My advice is to grab hold of people that are close to you and lean on them heavily. That's how we're designed to work!

Innovation is not about products or scientific laboratories- it is also about governance, education and everything we do as people. It is not about scientists alone innovating.