DNA is not life. A single chemical molecule has nothing to do with life. DNA is merely a storage system. Nobody would ever say that the "Divine Comedy" is the actual paper and ink on which one of its copies is printed, however many influential scientists have supported this nonsensical viewpoint.

Consider for instance that the bulk of the world's foreign exchange reserves – trillions of dollars – are held by developing economies, and that the US runs a current account and budget deficit of astronomical proportions.

If you're doing anything for legacy, you might as well forget about it – even your great grandchildren will have no idea who you were or what you did. Legacy lasts 50 years maximum.

A fantastic business stumbles onto something psychological which just gives it a fantastic edge. Netflix's killer psychological hack was 'have 3 DVDs at any one time, watch them as often as you want, change them out as often as you want, £19.95 a month. No late fees ever.' That turned into a business worth billions.

Even today, there are 72 countries and jurisdictions where same-sex relations are criminal acts – punishable with penalties ranging from a few years in prison, to life imprisonment and even the death penalty.

Having grown up and worked in this environment, I strongly believe there is a solution to everything as long as you are not willing to accept a status quo and constantly look for better results.

I flew home with this profound sense of the simultaneity of human suffering; I've never been able to get over that sense that even as I'm talking to you right now, there are people who are living unbearable lives.. I just came home and tried to think of as many ways that comedy could contribute – stage shows, television shows, books, merchandise, everything that we could do, like running a business.

Growing up in West Virginia, we were at the forefront economically— the chemical and coal mining center of the world. However, due to an inability to adapt to changing market dynamics and transitions, our position plummeted to the bottom ranks among the US states... I firmly advocate the idea of reinventing oneself every 5 years.

The real culprit behind the sickness often goes unnoticed: it's the disruption to our circadian rhythm caused by traveling across time zones. Our bodies are designed to operate on a natural rhythm.

In the West, politicians will say anything and not care about it- they'll be out of office by the time they would be held to account. The Chinese tend to under-promise and over-perform, they don't want to lose face.

What I realised was, that in studying other manufacturing companies, in particular Toyota, I could see that their mechanism for distributing responsibility and pushing it far down the organisation turned them into a creative enterprise! This is the opposite of what most people think, which is that the purpose of manufacturing is to reliably produce the same thing over and over again.

Imagine if Coca Cola said, 'well, we *could* take the sugar out of our drink, but how else would we give the world diabetes?' – we have information diabetes.