Much of the pushback against science is related to a distrust of the establishment and of multinational corporations and their profit motive. It's easy to spread fear; as humans we're very tuned and sensitive to it.

Our brains are not so well equipped, we just tend to assume patterns that look connected are causally connected. So a conspiracy theory is just another causal theory – why did these things happen?

There is a phrase, tell me what you pay attention to, and I will tell you who you are. That is how I would see the quest for authenticity.

Our core belief is in the immense potential of technology as a force multiplier, particularly when it's rendered accessible and intuitive. From the onset, we have viewed the internet through the lens of software, rather than merely brochureware.

You create change in other people when you're totally honest, transparent, and authentic. When you show people who you really are, with all your flaws, with all your vulnerabilities…it moves them.

You may become rich, engage in philanthropy and help a million people but the only way you can help a billion people is by building a profitable business. If you can't make a profit, you can't help a billion people – so go make a profit!

What I mean by that is compensation systems- especially for traders- that created go for broke incentives. If you won big, you became fabulously wealthy- and if you lost big- you got a comparative slap across the wrist.

The danger is that when we jump too quickly to the solution, not only is the floor littered with the inventions that never worked, but we risk designing solutions that never fit the problem.

If you go to any rave, or any football event, you will find people chanting in a rhythm- human beings do that. We have this sense to participate and organise- Music lets you rediscover your humanity, and your connection to humanity. When you listen to Mozart with other people, you feel that somehow- we're all in this together….

We've transformed HIV from a death sentence to a manageable chronic condition, but prevention remains our greatest challenge. We need to reach the most vulnerable populations with the tools we have.

When it comes to guns, the trend of covering of mass-shootings leads the public to think the big problem is mass shootings. However, the big problems are suicides, domestic violence, known people, and gangs shooting at each other.

The idea of selfish philanthropy is a push against the notion of philanthropy as simply 'giving back.' That phrase implies that wealth was accumulated by taking something from society. But if you've built a successful business, you've contributed to society—you don't owe anything back.