Growing up in Pakistan, I saw so many people with heart disease and having heart attacks – it felt almost biblical – it was catastrophic. Unlike a lot of diseases, there wasn't much a cultural footprint for heart disease – it's not something you hear about on news or TV shows…. You don't see much advocacy done around it.

I think that if you care about something, then you have a mission. Knowing that, and that your specific set of skills and experience brings something special to that mission, are key.

Over half have changed national policy within five years of launch.

Like everyone, investors get hurt by the implicit loss of purchasing power of each dollar inflation implies. However that is only the tip of the iceberg, as this loss is likely to be compounded by the tendency for traditional investments to suffer additional erosion.

I think the answer, really, in my view, is that we cannot control them because they are smarter. As simple as that, we only know that the smartest hacker in the room will always find a way through our defences. So maybe we should stop our arrogance for a minute.

Politics is not about management – it's about creating a narrative that can inspire and can bring people along in a certain direction.

As a leader, you must evolve with the role. When I was 22, 23, 24, I was learning what it meant to be an entrepreneur and a CEO, it felt like I was spinning out of control. My identity, and that of the company, were one-and-the=same, and that's not just inaccurate, it's unhealthy. Once I was able to separate my identity from the business, it got me really focussed on how I could become a better leader.

You have to know who you are, be open-minded, and be ready to collaborate. You have to have thick-skin and be prepared to get your idea ripped apart.

One of the amazing things is how adaptable our brains our – and by day 2, I was feeling really good. NASA is pretty good at understanding how to keep you healthy in space; and so you go through sleep-shifts to help you stay rested, and to make sure you don't get a drop in performance from being tired.

The most vivid character of our time has been the enslavement of society to this profiteering system.

Nothing prepares you to actually see the Earth from space. I spent more than 7 months in space, and even on my last day that view never got old.

If history has taught us anything, it's that women rarely win anything without a fight!