Confidence, after all, is simply one's belief in their own ability to accomplish a task or achieve a result. It's an elusive and abstract feeling. In my experience, many of the individuals I work with, including Olympians, often lack this so-called essential trait. My approach is always to redirect their focus from this nebulous concept of confidence to the concrete tasks at hand.

I tell people to activate their inner honey badger. Even your professor should not be free from criticism.

There was really a sense that humanity had already reached its peak, and so the question wasn't what comes next that's better, but rather how to prevent decline and loss. If you had a good state—or even just an okay one—your main concern was to keep it, to stop it from falling apart. Because there wasn't anything better you could reasonably expect.

Human progress often comes at great cost to people who are willing to sacrifice for the sake of principles or in defense of the rights of others. It took hundreds of millions of people to die before we created a global security and human rights order and all of these are under stress. One would hate to think it would be another similar amount of deaths before we made more progress.

Just because a decision doesn't work out doesn't mean it was the wrong decision. If it was based on the best available information at the time, it was still a sound choice.

There is a famous Iraqi idiom which states that if you think your opponents can eat you for dinner, then you'd better eat them for lunch. If your opponent is too big and powerful to eat you right-now, you'd better eat them for lunch before they eat you. Commitment problems from our opponents lead us to act, and that's another reason why rational man can go to war.

Public health is mostly a field for research and inquiry, but it's also an arena for action. The best way to think of public health as to see it tackling the health needs of an entire population rather than individuals (that is mostly what medicine does). I am a physician, but when I went into public health I said that my position was now that society would be my patient.

Politicians, by and large, don't understand technology at all, and technologists don't understand politicians—and both tend to denigrate each other. The technologists in Silicon Valley see politicians as venal, short-term, and ignorant, while politicians view technologists as rapacious capitalists who will stop at nothing to beat their rivals and lack any ethical compass.

When you put cells in the same vat and ask them to grow and they're producing ammonia, you're going to have a nice glass of urine! We must solve all of that!!

For me- I think we're all here to uplift the human condition, making lives better for ourselves and others.

I don't care about legacy, it's an old idea because we don't consume time like we did before. Time is now simultaneous – before, it was linear. Today it is a wall in front of us. When time is a wall, there is no place for legacy.

The industrial age was designed around one group of people making decisions, and a different group carrying them out. That mindset still lingers in our language — 'leaders' and 'followers,' 'blue collar' and 'management,' 'union' and 'executive.' It splits the world into thinkers and doers. That no longer works.