You have to go into a very quiet place in your mind, away from the noise of the world, the noise of doubters, insecurities and your own self. You have to quiet your disbelief and create open mindedness to your own ability to succeed and overcome.

Art, for him, is a crucial means for turning thinking into doing in the world.

I'm not saying that we should take-on less stress… the problem with the narratives around hustle-culture is that these narratives operate on one paradigm… you should either be working really hard, nor not working too hard.. that's a really primitive conversation. To be successful, you have to overcome a level of stress that would break most people. Building a company is not a sprint, it's a marathon… if you look at the world's best marathon runners, they're running in 4 minute miles. You have to learn how to take on an incredible amount of stress, and sustain it for a really long time.

At Colossal, we are not going to work in humans or non-human primates because we felt like we're already going to have an uphill battle with transparency and education, and we don't want people to be like, if a hair-loss treatment comes out of Colossal, 'are they selling a gene from a woolly mammoth?'

I don't think it's money that corrupts people, I really don't. I think it's the idea that when you make money without having a tangible creation attached to that money, it has no value.

Our research over the past 45+ years shows that when you're actively noticing, your neurons are firing, and that's literally and figuratively enlivening. And what do we do when we're having fun? We notice, we engage. So mindfulness is not just beneficial—it's enjoyable.

I tried to remain as emotionless as possible – remaining as much of a scientist as I could be, going with the evidence. I felt that although I didn't have a coach on hand in Ireland, and even though the sport of MMA was very small, I had mountains of evidence I could study.

You have to re-earn your customer's business every single day – it's not just about listening to them, but anticipating what they don't realise they need, and staying ahead of them.

My wife Freada coined a phrase, distance travelled. We're very interested in where somebody started in life, and what hurdles and barriers they have already overcome in their journey – and how that grit has got them to where they are now.

I have learnt that situations in themselves are not inherently stressful. Our perception of situations is what creates stress for us. Some players thrive in the biggest sporting occasions and others struggle to cope.

If you look at the balance sheets of Fortune 500 companies 50 years ago and today, 50 years ago, 80% of the value was physical stuff. Today, more than 85% of the value consists of intangibles. Companies must become so much more now that their value comes from their ability to inspire, drive and organise human beings.

There are multiple connections between human beings and music. Most fundamentally- we respond emotionally to music- sound is communicative, it affects us, it causes feelings and connections. Sound making and listening are communal activities, they're communicative activities… music moves us, and when we listen to it, we feel transported.