In comparing alternative explanations, it is not necessarily the one with the most evidence apparently in its favour that we should choose but the one with least evidence against it. One solid piece of evidence can demolish a hypothesis.

The standard models were formulated through a process that started well before computers were in place, and I would say it's undergone a certain lock-in. Once you start going down that path, it's hard to break out of it to another path. As a result, economics is stuck. It's not even that the existing models are wrong, they're just very limited in what they can do, and mainstream economists have gotten very locked in to using those models – and only those models.

To be an entrepreneur, you need a love for process and to be comfortable with adversity. If you love process and you're comfortable with adversity, and if you love the journey over the fruits and riches of that journey- then you have what it takes to be a successful entrepreneur.

Those anxieties have been largely invented as an answer to an internal threat Putin was facing. He knew the Russian people have been getting fed-up of Putinism, and that has to be a major factor in the invention of this external threat.

I didn't have a childhood- I didn't play- every day was about survival. I was always moving to a different-place on a weekly/monthly basis.

Anti-goals are all about what you refuse to give up while chasing those goals. The trap a lot of people fall into is getting so laser-focused on the target that everything else just fades away. You put on blinders.

Think about a rabbit sitting in a field. If that rabbit saw a hawk circling above and decided to wait for the back-propagation step before responding, it would be dead. The better you model the world, and the faster you can act on that model, the more likely your genes are to survive.

When you contrast that with human rights defenders, they are willing to self-sacrifice, to give everything to defend the community… not just their community, but everyone's rights. Why can't politicians be like that?

If you ask an American where the DJIA or Facebook is trading today, everybody knows. Ask the same person how many kids dropped out of high-school last year and nobody knows. That to me is very short sighted, after all what is the better barometer of the future of America?

If dementia is preventable, it means we're changing the trajectory of cognitive decline — which means that trajectory isn't inevitable.

The way to think about informational asymmetry is market by market. If you're in a supermarket buying lettuce, there are potential informational asymmetries. Someone may have used a bad fertiliser… even a toxic one… and you wouldn't know it staring at a piece of lettuce.

Western civilisation has veered off course; we have de-sacralised the world in which we live. We are collectively insane, and we need to mount our own intervention.