We humans are a musical species no less than a linguistic one. We integrate all of these and 'construct' music in our minds using many different parts of the brain. And to this largely unconscious structural appreciation of music is added an often intense and profound emotional reaction to music.

I think that's why I've always felt comfortable in the arts where you are creating things that will hopefully be around for a long time and won't be transient.

More than just being a luxury item, they are pieces that represent milestone moments- that's why they're important.

There's a moment when the unconscious crystallises into consciousness, leading to all our thoughts, feelings, and emotions. In ancient texts, this moment is referred to as 'vedana', and we describe them as 'feeling tones.' These feeling tones are the mind's initial acknowledgment or categorisation of experiences as pleasant, unpleasant, or neutral.

I can illustrate the current situation in the form of a story. Two boys were being chased by a Tiger. One boy stops to put on running shoes, and the other boy says, 'What are you doing?' The first boy responds, 'I don't have to outrun the Tiger, I just have to outrun you'.

I've done the show with a blown-out back, with one leg, coming off laryngitis, coming off or having a 103 degree fever. The bottom line is this… I go in there to do my job – the men and women fighting are actually putting their lives on the line – I'm just announcing! They're taking punches in the face, I'm just holding a microphone! I have nothing to complain about or make excuses for, the show must go on!

We were both passionate that we wanted to really make a difference; soup kitchens are good, but they don't prevent homelessness. You can go to volunteer at a soup kitchen every day of the year, and you'll still have homeless people. We wanted to tackle root causes and tackle them globally.

Cancer, we now know, is a disease caused by the uncontrolled growth of a single cell. This growth is unleashed by mutations- changes in DNA that specifically affect genes that incite unlimited cell growth. In a normal cell, powerful genetic circuits regulate cell division and cell death. In a cancer cell, these circuits have been broken, unleashing a cell that cannot stop growing.

It's sad that we don't immediately see the profound injustices embedded in climate change. It is precisely those people who have no responsibility for having caused climate change who are the most vulnerable to the negative impacts of climate.

The movements that sustain themselves the best over time are those that have culture at their core, that use art as a means of conveying a message, and use art-making as a means to mobilise a movement.

A regional war in say, South Asia, which involved as few as one hundred nuclear bombs would result in firestorms in their urban centres that would put so much smoke and particulate into the atmosphere that the earth would be covered in a cloud that would reflect sunlight back into space and reduce global temperatures but two to three degrees for several years. This would kill most food crops on the planet, resulting in massive famines and starvation.

Western civilisation has veered off course; we have de-sacralised the world in which we live. We are collectively insane, and we need to mount our own intervention.