That was when I thought, 'am I going to be someone who only wants to do music when it's all going well? And only when it's served to me on a plate? Or do I want to do this… no matter what…' For me, there was nothing else, I wanted to make music.

The concentration of power in technology corporations is a moral and political problem that we simply don't have a precedent for. More people use Facebook than speak English for example, so the implications of Facebook, as just one platform, are at the scale of language itself.

We're the mammal that likes Tabasco sauce! We're the only creature (as far as we know) that seeks out suffering and pain willingly. We do so not just through liberal splashes of Tabasco on our food, but also through seeking meaning through activities.

In the tech sphere, when you acquire a company, you're seldom buying the present product. Instead, you're investing in their future innovations. This means retaining talent is paramount.

The diversity of strategies people use is truly remarkable, I saw people using completely different strategies to the degree that if I had set out to invent 15 different strategies for a fictional work…. I couldn't have made the strategies more different to the ones I saw in real life! This illustrates a point I have made in all my works insofar as there really is no 'holy grail' or single style that is most effective.

We can win in the struggle to avoid climate chaos, we can win in terms of economic recovery and we can win when it comes to promoting development and justice. All we need is the political will.

It's a roll of the dice whenever one of these novel viruses emerges; sometimes they will be severe and contagious enough to cause a problem, and this one is.

Twitter, Facebook and Instagram were play attention games – they reward creators with 'status points,' likes, retweets and quote tweets for example. Those rewards come to those who are best at monopolising attention… that's not the same thing as telling the truth or acting in good faith. The things that get rewarded in those systems are things that provoke, divide and drive outrage – so we end up with a broken media economy that drives us all crazy and doesn't represent the best version of ourselves.

We are scientifically naked in front of this threat. We do not have the diagnostics to quickly detect an MDR or XDR case. Once detected, we do not have the drugs to effectively treat the patient at reasonable cost, and we do not have a TB vaccine.

In the business world, we need to focus on the 4-Cs. Firstly, Customer. Secondly, Competition. Thirdly, Comfort. It doesn't matter how successful you are, how much market share you have, if you're in your comfort zone you will leave yourself exposed. Fourth, Courage. You have to be prepared to take tough decisions. Cowardice pushes the day of reckoning out, decisiveness brings it closer.

Entrepreneurship is the relentless drive to carry-on, no matter what. Entrepreneurship is tolerance, focus and dedication. Entrepreneurship is this 'true north' belief that whatever this 'thing' is that you want to bring to culture, that you will see it through… and that you are the one here to usher it into existence.

The job of an entrepreneur or a competitive leader is to create the conditions that make your organisation the better competitive alternative. All your efforts should be directed towards marshalling and channelling resources—human and intellectual capital—towards being the best competitive alternative.