From 600+ conversations with the world’s leading thinkers.
What makes HIV so challenging is its ability to integrate into the host genome and establish latency. This is why we haven't been able to cure it yet - the virus literally becomes part of us.
There will be no cure for cancer until real doctors with real patients in real hospitals can attempt an innovation.
The basic problem is that if you attempt to commit suicide with a gun, you typically succeed. It's also true that there is a more violent culture generally in the US. The US in general, has broader problems with crime, with social dysfunction, narcotics often, and all these work together with guns to create this epidemic.
Alzheimer's starts its destructive process 30 years prior to its typical diagnosis. Therefore, when considering the prevalence of this disease, we're speaking of 7 million diagnosed patients in the US. But then, one might ask, how many Americans currently have the initial stages of Alzheimer's, characterized by amyloid plaques, cell death, tangles, and inflammation, already festering in their brains? I concur with the higher estimates, suggesting around 40 million people.
The most important versions of love and compassion are the ones we show to ourselves. We have to start there. It's not selfish or ignorant. If you don't make space for yourself to feel loved by you, the rest is impossible… you'll always end up burned-out or in a state of resentment.
Whether it's doodling with a pencil, or painting, the practice of art – in any shape or form – is hugely liberating and gets us into the sense, and state, of flow. Art helps us navigate our place in the world, and offers us a place of stillness – much needed in today's digital world.
If someone's brain isn't at its healthiest, their decisions won't be as stellar as they could be, potentially costing them thousands, even millions, of dollars. For leaders, it's crucial to nurture the 'chief executive' part of the brain, the frontal lobes.
Limiting sleep to just 4-5 hours for one single night will drop levels of critical anti-cancer fighting cells, called natural killer cells, by 70%. That's a rather alarming state of immune deficiency, and it happens after just one night of short sleep.
Our boredom threshold has declined to the point where we're unable to stand idle in an elevator for ten seconds without pulling out our phones. There's also an epidemic of social avoidance, particularly among younger people, as the skills required for face-to-face interaction are more demanding.
We spend so much time at work, so we're going to have relationships with our colleagues – and those relationships may be distanced, troubled or fantastic. When they're positive, they're a source of joy, energy, productivity, and resilience. On the flip side, when those relationships are negative or stressful, they have incredible ramifications for our well-being, productivity, and creativity. Studies show that even when we cut ourselves, it takes longer to heal if we are having animosity in our close relationships!
That experience [of being tortured] has altered my whole life. You can never be the same person and anything you do is in reference to that moment. I have never been able to pass it.
We got to the point where, we are not on our grandparents' planet anymore. Meat has become less healthy for us – it's too available. There are too many calories, too much saturated fat. Animals are no longer 'free-rangy', they are growing in very tight confined conditions.