The key both in the US and the UK is to have hand-raisers – people who want to take a chance, and get involved. That is a spirit that you see both in the UK and in America.

It's a very precarious situation we're in right now; and the biproduct of our current policies is that a tidal wave of radioactive social problems is coming. I worry that we'll just repeat the mistakes of the past where drug addictions, drug related deaths, alcoholism and suicide spike out of control.

Those cycles don't exist – that's not what history is like. Disasters keep coming along at random intervals, they are not normally distributed... That's hard for our brains to deal with… we don't like the idea that history is just a lot of random shocks without any predictable features.

Change proceeds at the speed of trust. Building this trust, particularly in the context of AI and synthetic biology, starts with open information exchange, discussion, and dialogue. It's about creating a shared understanding of our capabilities, responsible deployment of technology, and acknowledging the associated risks.

The last quarter century of globalisation has utterly transformed how our markets and nations do business. With that in mind, we have to appreciate that our economies not only provide profound benefits and wealth-creation opportunities, but also hold very real (and untended) existential threats to the livelihoods of billions of citizens.

One is: Do I trust you with my feelings? Do I think that you're going to be a listener who is non-judgmental, or do I think you're going to judge me—'Marc is weak because he's anxious,' or 'Marc is a man and he's feeling sad; dudes don't feel sad.' So if I think you're going to judge me for my feelings, I'm going to be much more guarded about whether or not I express them.

It was her death that actually made us say 'right, that's it – we've talked a lot but we haven't done anything. Now we've got to do something'. And that's when Zoo Check began which is what we were called in those days.

Only a handful of diplomats and governments are prepared to put the global good before the national interest. Seldom is it the case for any diplomat that they put the global good high up on the agenda; in my career I've seen it very rarely. Only 30 of the 193 or so ambassadors at the UN in NY will be devoted to a multilateral context. Most are pursuing bilateral interests in a multilateral context.

Research shows that empowering women to gain financial independence generates lasting impact, with women typically investing 90% of their income back into their families. In addition to this, McKinsey estimates that if women and men were to play an identical role in labour markets across the world, an extra $28 trillion would be added to the global economy by 2025.

In the West, politicians will say anything and not care about it- they'll be out of office by the time they would be held to account. The Chinese tend to under-promise and over-perform, they don't want to lose face.

The minute they had a job, the minute they started working, that's when they lost the sense of being a refugee and became part of the community. That was the moment they started to regain their dignity and became independent.

The displacement that people face is now over generations not just years. The old model was to keep people alive until they go home. That model is broken, less than 3% of the world's refugees went home last year.